Včasné provedení PTA u diabetiků s defekty na nohou

Title in English Timely Implementation of PTA in Diabetic Patients with Defects in the Leg
Authors

HOFÍREK Ivo KONEČNÁ Jana VOJTÍŠEK Bohuslav STAFFA Robert ŠÁRNÍK Stanislav SOCHOR Ondřej ROTNÁGL Josef

Year of publication 2010
Type Appeared in Conference without Proceedings
MU Faculty or unit

Faculty of Medicine

Citation
Description Aim: Compared to patiens with diabetic angiopathy by the time the implementation of endovascular interventions. Metod: 59 patients with diabetes II. type with affected tibial arteries with 1 stable defect in the legs (region MTP) or toes. Group A, 33 patients with duration of the defect on average 14 +- 2 weeks, and group B, 26 patients with defects existing 6 +- 1 week. Patiens were performed PTA on tibial arteries with stenosis. The average carried 4.2 +-1.6 dilation on 1,9 +- 0,9 arteries. Patients with closures arteries were not included in the file. Patiens had sustained dual antiplatelet therapy (ASA 100 mg / day and clopidogrel 75 mg /day or ticlopidine 400 mg / day). Results: 9-12 months after PTA were cured or diminished (> 75%) defects in 13 patients (39%) group A and in 19 patients (73%) in Group B, (p< 0.05). Virtual flow in the distal parts of the tibial arteries after PTA in both groups improved similarly increased by about averages 19.5 +- 8.9 ml / min (n.s.) Peripheral vascular reactivity appeared to trend towards improvement in group B, otherwise the groups did not differ. Group A vs. Group B 29.9 +-19.1 v. 49.1 + -19.5 PU (p< 0.05) HbA 1c in the PTA group did not differ and amounted to 8.1 +- 2.2%. After 9 to 12 months the values were in group A 8.0 + -1,9% and in group B 7.8 + -1,5% (ns). In 5 patients in Group A were within 6 months after the intervention for the deterioration and the development of other defects on the leg performed surgical revascularisation procedures. Conclusion: Earlier implementation of PTA, group B, at the same podology care had higher probability of healing defects.

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