Determination of asialotransferrin in the cerebrospinal fluid with the HPLC method
| Authors | |
|---|---|
| Year of publication | 2010 |
| Type | Article in Periodical |
| Magazine / Source | Scandiavian Journal of Clinical & Laboratory Investigation |
| MU Faculty or unit | |
| Citation | |
| Doi | http://dx.doi.org/10.3109/00365510903521559 |
| Field | Traumatology and orthopaedic surgery |
| Keywords | Asialotransferrin; cerebrospinal fluid; HPLC; mass spectrometry |
| Description | Identification of the content of asialotransferrin in the cerebrospinal fluid is a diagnostic method for childhood-onset ataxia and central nervous system hypomyelination (CACH), also known as vanishing white matter disease (VWM), and also for other types of CNS disorders. Methods: In our work, we have determined the value of the ratio of the asialo form of transferrin to the total transferrin in the CSF using the commercially used Variant |