Kryoglobulinémie a její rizika při laboratorním vyšetřování-kazuistika
| Title in English | Cryoglobulinemia and its risks on laboratory examination - case report |
|---|---|
| Authors | |
| Year of publication | 2009 |
| Type | Article in Periodical |
| Magazine / Source | Klinická biochemie a metabolismus |
| MU Faculty or unit | |
| Citation | |
| Web | |
| Field | Biochemistry |
| Keywords | cryoglobulinemia,cryoprecipitate,protein electrophoresis, monoclonal imunoglobulin |
| Description | Cryoglobulinemia is characterized by presence of abnormal plasma protein. This protein reversibly precipitates upon cooling and causes variety of peripheral vascular manifestations. Cryoglobulins are found in association with broad spectrum of diseases. We reported case suspected of cryoglobulinemia. Blood specimens were drawn, transported and investigated at temperature 37 degrees Celsius. Serum assigned strong cryoprecipitate properties.Unexpectedly there were no abnormalities on electrophoresis of serum proteins.Protein electrophoresis was made once more after incubation with mercaptoethanol and in this case we could see peak of monoclonal protein there. |