Enhancement of psychostimulant effect and development of behavioural sensitisation to methamphetamine in mice by combined treatment with piracetam
| Authors | |
|---|---|
| Year of publication | 2011 |
| Type | Article in Periodical |
| Magazine / Source | Activitas Nervosa Superior Rediviva |
| MU Faculty or unit | |
| Citation | |
| Field | Pharmacology and pharmaceutical chemistry |
| Keywords | methamphetamine; piracetam; behavioural sensitisation; mice; open field test |
| Description | Piracetam in our experiment enhanced acute effects of methamphetamine as well as development of sensitisation to its stimulatory effects. Background of these pharmacological drug-drug interactions remains unclear. Although clinically piracetam itself shows minimal adverse effects and toxicity, its combination with methamphetamine could worsen the negative drug abuse consequences. |
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