Cetuximab v kombinaci s radioterapií jako metoda volby v první linii léčby lokoregionálně pokročilých karcinomů hlavy a krku - případy z praxe
| Title in English | Cetuximab in combination with radiotherapy as method of choice in first-line treatment for locoregionally advanced head and neck cancers – cases from practice |
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| Authors | |
| Year of publication | 2011 |
| Type | Article in Periodical |
| Magazine / Source | Klinická onkologie |
| MU Faculty or unit | |
| Citation | |
| Field | Oncology and hematology |
| Keywords | cetuximab; HNSCC; locoregionally advanced head and neck cancers; double tumour; organ-preserving protocol; predictive markers; K-ras |
| Description | Cetuximab whose lower toxicity is a clear benefit compared to chemotherapy is the only agent registered for the targeted therapy of squamous cell head and neck cancers. Given the high complete remission rate in locoregionally advanced disease in our cohort, our experience with this treatment is very good. In addition to clinical observation, research into predictive markers is under development. |