Mikroprostředí kostní dřeně a jeho role v patogenezi leukemií

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Title in English	Bone marrow microenvironment and its role in the pathogenesis of leukaemia
Authors	LÉTALOVÁ Eva DOUBEK Michael FOLBER František VERNER Jan MRÁZ Marek POSPÍŠILOVÁ Šárka MAYER Jiří
Year of publication	2011
Type	Article in Periodical
Magazine / Source	Transfuze a hematologie dnes
MU Faculty or unit	Central European Institute of Technology
Citation
Field	Oncology and hematology
Keywords	haematopoiesis; bone marrow microenvironment; haematopoieticstem cell niche
Description	Bone marrow microenvironment plays a key role in the process of haematopoiesis. It has a supportive function for quiescent haematopoietic stem cells located in so called niches. It provides appropriate conditions for haematopoietic stem cell differentiation and for the proliferation of blood elements.