Combination of fertility preservation strategies in young women with recently diagnosed cancer

Authors

HUSER Martin ŽÁKOVÁ Jana ŠMARDOVÁ Lenka CRHA Igor JANKŮ Petr HUDEČEK Robert VENTRUBA Pavel

Year of publication 2012
Type Article in Periodical
Magazine / Source European Journal of Gynaecological Oncology
MU Faculty or unit

Faculty of Medicine

Citation
Field Gynaecology and obstetrics
Keywords Cancer; infenility; Fenility preservation; Oocyte cryopreservation: Ovariall tissue cryoprescrvation
Attached files
Description The study describes clinical management and outcomes of currently available fertility preservation techniques in a set of 154 young female cancer patients. Metlwds: Patients in reproductive age with newly diagnosed cancer were offered embryo or oocyte cryopreservation, ovarian tissue cryopreservation and the administration of GnRH analogues during chemotherapy. Particular attention was given to the technical aspects and clinical application of these fenility preservation techniques. Resuils: During the study period (2004-2009), 154 young female cancer patients were offered fertility preservation counseling. Patients average age was 29.4 years and average parity was 0.7 children. Administration of GnRH analogues and ovarian tissue cryopreservation were the most commonly used fertility preservation strategies. In 20 cases (16.1 %). the combination of several fertility preservation techniques was offered to individuaJly selected patients. Conclusions: Combination of fertility preservation techniques gives young cancer patients the best chance for future fertility and should be concentrated in specialized centers.
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