Project information
Mutační analýza primitivních buněčných populací u chronické myeloidní leukémie: za hranicí BCR-ABL1

Information

This project doesn't include Faculty of Medicine. It includes Central European Institute of Technology. Official project website can be found on muni.cz.

Project Identification

17-30397A (kod CEP: NV17-30397A)

Project Period

4/2017 - 12/2020

Investor / Pogramme / Project type

Ministry of Health of the CR

Ministry of Health Research Programme 2015 - 2022

MU Faculty or unit

Central European Institute of Technology

RNDr. Marianna Romžová, Ph.D.

Cooperating Organization

University Hospital Brno-Bohunice

Responsible person prof. MUDr. Zdeněk Ráčil, Ph.D.

Mutační analýza primitivních buněčných populací u chronické myeloidní leukémie: za hranicí BCR-ABL1

Publications

Total number of publications: 9

2021

Digital PCR can provide improved BCR-ABL1 detection in chronic myeloid leukemia patients in deep molecular response and sensitivity of standard quantitative methods using EAC assays

SMITALOVÁ Dagmar DVORAKOVA D. RÁČIL Zdeněk ROMŽOVÁ Marianna

Article in Periodical

Practical Laboratory Medicine, year: 2021, volume: 25, edition: MAY, DOI
Hierarchical distribution of somatic variants in newly diagnosed chronic myeloid leukaemia at diagnosis and early follow-up

ROMŽOVÁ Marianna SMITALOVÁ Dagmar HYNŠT Jakub TOM Nikola LOJA Tomáš HERUDKOVÁ Zdeňka JURČEK Tomáš STEJSKAL Lukas ŽÁČKOVÁ Daniela MAYER Jiří RÁČIL Zdeněk ČULEN Martin

Article in Periodical

British journal of haematology, year: 2021, volume: 194, edition: 3, DOI

2020

Analysis of serum lipids, cardiovascular risk, and indication for statin use during nilotinib and imatinib therapy in de novo CML patients ? results from real-life prospective study

HORŇÁK Tomáš SEMERÁD Lukáš ŽÁČKOVÁ Daniela WEINBERGEROVÁ Barbora ŠUSTKOVÁ Zuzana PROCHÁZKOVÁ Jiřina BELOHLAVKOVA Petra STEJSKAL Lukas ROHON Peter FABER Edgar ZAK Pavel MAYER Jiří RÁČIL Zdeněk

Article in Periodical

LEUKEMIA & LYMPHOMA, year: 2020, volume: 61, edition: 2, DOI
Novel Illumina-based next generation sequencing approach with one-round amplification provides early and reliable detection of BCR-ABL1 kinase domain mutations in chronic myeloid leukemia

ROMŽOVÁ Marianna SMITALOVÁ Dagmar TOM Nikola JURČEK Tomáš ČULEN Martin ŽÁČKOVÁ Daniela MAYER Jiří RÁČIL Zdeněk

Article in Periodical

British journal of haematology, year: 2020, volume: 189, edition: 3, DOI

2019

Analysis of gene expression in CD26+ CML leukemic stem cell population.

SMITALOVÁ Dagmar LOJA Tomáš ČULEN Martin HERUDKOVÁ Zdeňka BUDINSKÁ Eva MAYER Jiří RÁČIL Zdeněk ROMŽOVÁ Marianna

Conference abstract

Year: 2019, type: Conference abstract
Gene expression profiling of CD26+ leukemic stem cell population from CML patients.

SMITALOVÁ Dagmar ČULEN Martin HERUDKOVÁ Zdeňka BUDINSKÁ Eva MAYER Jiří RÁČIL Zdeněk ROMŽOVÁ Marianna

Conference abstract

Year: 2019, type: Conference abstract

2018

Insulin resistance is an underlying mechanism of impaired glucose metabolism during nilotinib therapy

RÁČIL Zdeněk KORIŤÁKOVÁ Eva SACHA Tomasz KLAMOVA Hana BELOHLAVKOVA Petra FABER Edgar REA Delphine MALASKOVA Ludmila PROCHÁZKOVÁ Jiřina ŽÁČKOVÁ Daniela VOGLOVA Jaroslava WACLAW Joanna CETKOVSKY Petr ZAK Pavel MAYER Jiří

Article in Periodical

American Journal of Hematology, year: 2018, volume: 93, edition: 10, DOI
Ultrasensitive detection of TKI resistant mutations using Illumina NGS in chronic myeloid leukemia patients.

SMITALOVÁ Dagmar TOM Nikola JURČEK Tomáš MAYER Jiří RÁČIL Zdeněk ROMŽOVÁ Marianna

Conference abstract

Year: 2018, type: Conference abstract
Ultra-sensitive detection of tyrosine kinase inhibitor resistant mutations in chronic myeloid leukemia patients using Miseq Illumina next generation sequencing platform

ROMŽOVÁ Marianna SMITALOVÁ Dagmar TOM Nikola JURČEK Tomáš MAYER Jiří RÁČIL Zdeněk

Conference abstract

Year: 2018, type: Conference abstract