Vliv pneumologické medikace na funkce lidských kardiomyocytů
- Project Identification
- NU20-06-00156
- Project Period
- 5/2020 - 12/2023
- Investor / Pogramme / Project type
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Ministry of Health of the CR
- Ministry of Health Research Programme 2020 - 2026
- Subprogram 1 - standard
- MU Faculty or unit
- Faculty of Medicine
- Cooperating Organization
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University Hospital Brno-Bohunice
- Responsible person doc. MUDr. Kristián Brat, Ph.D.
Projekt se bude zabývat mechanizmem vzniku kardiomyopatie působením kombinací bronchodilatačních léčiv, za použití kardiomyocytů odvozených z pluripotentních kmenových buněk, získaných reprogramací primárních kultur z biopsií pacienů.
Publications
Total number of publications: 17
2023
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Cardiovascular Diseases
Volume 2 Biomedical Applications, year: 2023, number of pages: 26 s.
2022
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Aminophylline Induces Two Types of Arrhythmic Events in Human Pluripotent Stem Cell–Derived Cardiomyocytes
Frontiers in Pharmacology, year: 2022, volume: 12, edition: January, DOI
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Atomic Force Spectroscopy is a promising tool to study contractile properties of cardiac cells
Micron, year: 2022, volume: 2022, edition: 155, DOI
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DUAL CARDIOMYOCYTE CLUSTER ARRHYTHMIAS DETECTED BY ATOMIC FORCE MICROSCOPY
Year: 2022, type: Appeared in Conference without Proceedings
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Dual cardiomyocyte cluster detection the different types of arrhythmogenic potential of caffein
Year: 2022, type: Conference abstract
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Effects of salbutamol and ipratropium on human stem-cells derived cardiomyocytes’ function
Year: 2022, type: Conference abstract
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hESC derived cardiomyocyte biosensor to detect the different types of arrhythmogenic properties of drugs
Analytica Chimica Acta, year: 2022, volume: 1216, edition: July 2022, DOI
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Změny elektromechanických vlastností lidských kardiomyocytů v prostředí běžně užívaných bronchodilatancií – aminophyllin, salbutamol, ipratropium
Year: 2022, type: Appeared in Conference without Proceedings
2021
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[P3.065] Biomechanical drug testing by atomic force microscopy combined with human pluripotent stem cell derived cardiomyocytes
Year: 2021, type: Conference abstract
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Arrhythmic events in clustered human pluripotent stem cell-derived cardiomyocytes
Year: 2021, type: Conference abstract