Investigation of common and organ-specific mechanisms of epithelial morphogenesis regulation by fibroblasts (Role of fibroblasts in epithelial morphogenesis)

Project Identification
Project Period
1/2022 - 12/2022
Investor / Pogramme / Project type
Masaryk University
MU Faculty or unit
Faculty of Medicine

Epithelial-mesenchymal interactions play a crucial role in organ development. Mesenchymal cells, such as fibroblasts, provide crucial signals for epithelial morphogenesis, but their exact roles, both general and organ-specific, are incompletely understood. In this project, I will investigate the role of fibroblasts in mammary and lacrimal gland development using genetic mouse models to decipher common and organ-specific fibroblast functions.

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