Fenotypická konverze CYP 2D6 a sexuální dysfunkce

Title in English Phenotypic conversion of CYP 2D6 and sexual dysfunction


Year of publication 2002
Type Article in Periodical
Magazine / Source Klinická farmakologie a farmacie
MU Faculty or unit

Faculty of Medicine

Field Pharmacology and pharmaceutical chemistry
Keywords sexual dysfunctions-paroxetine-CYP 2D6-genetic polymorphism
Description The paper deals with the incidence of sexual dysfunction within the group of 30 patients on a long-term treatment with paroxetine in coherence with the activity of P 450 CYP 2D6.The stattistic comparison revealed significantly increased occurence of sexual dysfunction in patients with reduced CYP 2D6 metabolic capacity.
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