Does repeated treatment with MDMA sensitize to its effects on agonistic behaviour in mice?


ŠLAIS Karel LANDA Leoš ŠULCOVÁ Alexandra

Year of publication 2005
Type Article in Periodical
Magazine / Source European Neuropsychopharmacology
MU Faculty or unit

Faculty of Medicine

Field Pharmacology and pharmaceutical chemistry
Keywords behavioural sensitization; MDMA; agonistic behaviour; mice
Description In aggressive mice in both groups, vehicle and MDMA pre-treated animals, the drug caused highly significant inhibition of all aggressive activities with the significant increase of defensive-escape behaviour and ambivalent of walking. However, there were no significant differences between group sensitized with vehicle and the other one sensitized with MDMA.
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