Šance na vyléčení dětí s akutní lymfoblastickou leukémií stoupla v České republice v 21. století na 90 % – výsledky studie ALL IC-BFM 2002

Title in English	The prospects for children with acute lymphoblastic leukemia of being cured has increased in the Czech Republic in the 21st century to 90% - outcome of the ALL-IC BFM 2002 trial
Authors	ZDRÁHALOVÁ Kateřina ŠTĚRBA Jaroslav DOMANSKÝ Jiří BLAŽEK Bohumír PTOSZKOVÁ Hana MIHÁL Vladimír NOVÁK Zbyněk HAK Jiří PROCHÁZKOVÁ Daniela ČERNÁ Zdena TIMR Pavel JABALI Yahia SEDLÁČEK Petr SMÍŠEK Petr ZEMANOVÁ Zuzana JAROŠOVÁ Marie HOUDKOVÁ Alena MEJSTŘÍKOVÁ Ester HRUŠÁK Ondřej ZUNA Jan JANOTOVÁ Iveta TRKA Jan STARÝ Jan
Year of publication	2015
Type	Article in Periodical
Magazine / Source	Časopis lékařů českých
MU Faculty or unit	Faculty of Medicine
Citation
Web	https://www.prolekare.cz/casopisy/casopis-lekaru-ceskych/2015-2/sance-na-vyleceni-deti-s-akutni-lymfoblastickou-leukemii-stoupla-v-ceske-republicev-21-stoleti-na-90-vysledky-studie-all-ic-bfm-2002-51937
Field	Oncology and hematology
Keywords	acute lymphoblastic leukemia; children; chemotherapy; protocol ALL-IC BFM 2002
Description	Background. Acute lymphoblastic leukemia (ALL) is the most frequent childhood malignancy. Treatment has been unified in the middle of 1980 in the Czech Republic. In 2002-2007 children and adolescents with acute lymphoblastic leukemia were treated in an international randomized trial ALL-IC BFM 2002 in the Czech Republic. 291 patients aged 1-18 years were enrolled; infants below 1 year entered a separate trial. Conclusions. In comparison with the previous trial ALL BFM 95, significant improvement was achieved.