Epidemiologie a populační screening nádorů tlustého střeva a konečníku v ČR na podkladě nově dostupných dat

Title in English Epidemiology and population-based screening of colorectal cancer in the Czech Republic according to recent data


Year of publication 2015
Type Article in Periodical
Magazine / Source Gastroenterologie a hepatologie
MU Faculty or unit

Faculty of Medicine

Doi http://dx.doi.org/10.14735/amgh2015509
Field Oncology and hematology
Keywords Malign tumour; colon; rectum; prevention; screening; personalised invitation
Description In the long term, the Czech Republic ranks among the countries with the highest incidence and mortality rates for colorectal cancer (CRC) globally. Each year in the Czech Republic nearly 8000 people are diagnosed with CRC and there are approximately 3600 deaths from the disease. The prevalence of CRC patients reached almost 55,000 by 2013, and there is a 2–3% increase each year. Moreover, the prevalence involves a large proportion of patients diagnosed with advanced CRC, as more than 30% of CRC cases are diagnosed in clinical stages 3 and 4 each year. The high epidemiological burden itself justifies the need for an organised screening programme, which has a strong background in evidence-based medicine as regards this particular disease. The Czech National Colorectal Cancer Screening Programme has a sufficient capacity and is guaranteed by general practitioners, gastroenterologists and gynaecologists. Personalised invitations of Czech citizens to cancer screening programmes were launched in January 2014, and the programme has since transformed into the desirable regime of the so-called population-based screening. The response rate was 17.3% in the first round of invitations, and 11.8% in the second round of invitations. The screening coverage has increased significantly as a result of personalised invitations, reaching 30.8% in 2014 when taking into account the entire target population. Evaluation of the first stage of personalised invitations has again confirmed its significance and a positive impact on the prevention programme effectiveness. In the long term, the ongoing screening programme has influenced the main epidemiological trends, i.e. stabilised or even slightly decreasing incidence rates, and longer survival rates of CRC patients.
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