Gluten ataxia is better classified as non-celiac gluten sensitivity than as celiac disease: a comparative clinical study
| Authors | |
|---|---|
| Year of publication | 2016 |
| Type | Article in Periodical |
| Magazine / Source | Immunologic Research |
| MU Faculty or unit | |
| Citation | |
| Doi | http://dx.doi.org/10.1007/s12026-015-8750-1 |
| Field | Other specializations of internal medicine |
| Keywords | Gluten ataxia; Non-celiac gluten sensitivity; Celiac disease; Comparative study |
| Description | Gluten ataxia (GA) has customarily been considered to be the main neurological manifestation of celiac disease (CD). In recent years, the condition of non-celiac gluten sensitivity (NCGS) has been defined, which includes some patients who are not considered ‘‘true celiacs.’’ We performed a comparative clinicopathological study of these three entities. We studied 31 GA, 48 CD and 37 NCGS patients, prospectively in the same center for a period of 7 years. The protocol study included two serological determinations for gluten sensitivity [anti-gliadin IgA and IgG (AGA) and anti-tissue transglutaminase IgA (TG) antibodies], HLA-DQ2 typing, and duodenal histological assessment. Demographics and investigative findings were compared. |