Na jaké hodnoty snižovat systolický krevní tlak? Studie SPRINT
| Title in English | To what values should we reduce systolic blood pressure? The SPRINT study |
|---|---|
| Authors | |
| Year of publication | 2016 |
| Type | Article in Periodical |
| Magazine / Source | Kardiologická revue - Interní medicína |
| MU Faculty or unit | |
| Citation | |
| Field | Cardiovascular diseases incl. cardiosurgery |
| Keywords | systolic blood pressure; target values; cardiovascular events; hypotension |
| Description | There is no clear consensus about the optimal target value of blood pressure lowering that would reduce cardiovascular events and cardiovascular and all-cause mortality. Within the ACCORD study, intensive systolic blood pressure (SBP) treatment with target values under 120 mm Hg was compared with standardtreatment with target SBP values under 140 mm Hg, and a reduction below 120 mm Hg had no eff ect on the primary aim (i.e. all-cause mortality) in patients with diabetes mellitus. Now there is the SPRINT study, where results show a positive eff ect of intensive blood pressure lowering therapy on the combined primary aim that was defi ned as myocardial infarction, other acute coronary syndromes, stroke, heart failure or cardiovascular death; however, the results also show a statistically signifi cant increase in the occurrence of side eff ects (hypotension, syncope, renal injury or failure). |