Principy léčby chronické pankreatitidy
| Title in English | Principles of chronic pancreatitis treatment |
|---|---|
| Authors | |
| Year of publication | 2016 |
| Type | Article in Periodical |
| Magazine / Source | Gastroenterológia pre prax |
| MU Faculty or unit | |
| Citation | |
| Field | Other medical specializations |
| Keywords | chronic pancreatitis; treatment; pancreatic enzymes; analgesics; endoscopy; surgery |
| Description | Abdominal pain, exocrine and endocrine insufficiency are the most common symptoms of chronic pancreatitis. Conservative treatment options involve lifestyle modification, pancreatic enzyme substitution and analgesics. Adjunctive agents such as antidepressants, GABA analogues (gabapentin, pregabalin) and proton-pump inhibitors can alleviate disease symptoms. Small bowel bacterial overgrowth is treatable with antibiotics, preferably poorly absorbed rifaximin. Diabetes mellitus can be treated with oral hypoglycaemics or insulin depending on residual pancreatic endocrine function. Complicated cases require invasive treatment – radiological, endoscopic or surgical. Indications of surgery for chronic pancreatitis are intractable pain, symptomatic complications (pseudocyst, pseudoaneurysm, obstruction of adjacent structures) and doubt of malignancy. |