Oxidative stress in wound healing - current knowledge
| Authors | |
|---|---|
| Year of publication | 2019 |
| Type | Article in Periodical |
| Magazine / Source | Ceska a slovenska neurologie a neurochirurgie |
| MU Faculty or unit | |
| Citation | |
| Web | http://dx.doi.org/10.14735/amcsnn2019S37 |
| Doi | http://dx.doi.org/10.14735/amcsnn2019S37 |
| Keywords | reactive oxygen species; reactive nitrogen species; oxidative stress; wound healing |
| Description | Wound healing is a complex process based on a subtle coordination of biochemical and physiological interactions. Healing process itself and its quality are affected by numerous factors, both local (type, size, depth, and localization of the wound, bacterial contamination, microcirculation, oxygen supply, etc.) and systemic (age, comorbidities, smoking, nutritional status, etc.). Many studies, using various methodological approaches, focus on wound healing process at various levels. It is well known that reactive oxygen and nitrogen species play an important role in all phases of wound healing. Regardless increasing knowledge about the role of oxidative stress in wound healing process, the conclusions of research in this area are still rather contradictory. Therefore, aim of this paper is to summarize current knowledge about the role of oxidative stress in wound healing process. |