Day and night blood pressure variability during seven-day ambulatory blood pressure monitoring

Authors

SIEGELOVÁ Jarmila HAVELKOVÁ Alena FIŠER B. DUŠEK Jiří POHANKA Michal MAŠEK M. DUNKLEROVÁ Leona CORNÉLISSEN G. HALBERG F.

Year of publication 2010
Type Article in Proceedings
Conference Noninvasive methods in cardiology 20210
MU Faculty or unit

Faculty of Medicine

Citation
Web https://is.muni.cz/do/med/noninvasive_methods_in_cardiology/NoninvasiveMethods2010.pdf
Description The fact that raised nocturnal blood pressure predicted a higher rate of cardiovascular complications was established in several large-scale studies (1 – 6). Recently the investigators of the international Database on Ambulatory blood pressure monitoring in relation to cardiovascular outcomes (iDAco) did 24-hour blood pressure monitoring in 7458 people from Denmark, Belgium, Japan, Sweden, Uruguay and china and calculated cohort, sex, age, body-mass index, smoking and drinking, serum cholesterol, history of cardiovascular disease, diabetes mellitus, and antihypertensive drug treatment adjusted hazard ratios for day-time and night-time blood pressure (7). in fully adjusted models, the night-time blood pressure was additionally adjusted for day-time blood pressure. The subjects with mean age of 56.8 years were followed for approximately 10 years (median 9.6 years). Fully adjusted night-time blood pressure predicted total, cardiovascular and non-cardiovascular mortality. Results of all those studies indicated the necessity of 24-hour ambulatory blood pressure recording in clinical practice. Because the diagnosis of hypertension is generally based on casual measurement of blood pressure in general practitioner office and these values of blood pressure are higher than values of ambulatory blood pressure monitoring, the table of blood pressure thresholds for definition of hypertension with different types of measurement is included in the guidelines for Management of Hypertension (8). According to this table the threshold for systolic blood pressure is 140 mmHg in the office or clinic, 125 – 130 mmHg during 24 hours, 130 -135 mmHg during day and 120 mmHg during night. The corresponding values for diastolic blood pressure are 90 mmHg in the office and clinic, 80 mmHg during 24 hours, 85 mmHg during day and 75 mmHg during night. The values for home measurement are the same as for ambulatory monitoring during day. The condition for reliability of diagnosis is low day-to-day variation of night-time and day-time pressure values. The variation of night-time and day-time blood pressure during 7-day continuous ambulatory monitoring was the aim of the present study.

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