Blood pressure variability at rest and during exercise in healthy men: seven day ambulatory blood pressure monitoring
| Authors | |
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| Year of publication | 2014 |
| Type | Article in Proceedings |
| Conference | Noninvasive methods in cardiology 2014 |
| MU Faculty or unit | |
| Citation | |
| Web | https://is.muni.cz/do/med/noninvasive_methods_in_cardiology/noninvasive-methods-in-cardiology-2014.pdf |
| Description | Franz Halberg in his chronobiologic studies from Halberg University Center in Minnesota described the circadian rhythm and analyzed the risk of high blood pressure in appearence of cardiovascular diseases (1-8). In a 6 years prospective study of Kunaiki Otsuka on 297 patients, ambulatory monitored for 48 hours, circadian hyperamplitude tension (CHAT) was found to represent the largest increase in the risk of cerebral ischemic events, greater than increase in mean blood pressure, so called MESOR – hypertension, old age, a positive family history of high blood pressure, smoking, alcohol consumption (5). A reduced standard deviation (SD) from 24-hour measurement of heart rate was also associated with an increase of vascular morbidity, coronary artery disease and cerebral ischemic events (8). Because the diagnosis of hypertension (9-18) is generally based on casual measurement of blood pressure in general practitioner office and these values of blood pressure are higher than values of ambulatory blood pressure monitoring, the table of blood pressure thresholds for definition of hypertension with different types of measurement is included in the Guidelines for Management of Hypertension (2007). According to this table the threshold for systolic blood pressure is 140 mmHg in the office or clinic, 125 – 130 mmHg during 24 hours, 130 -135 mmHg during day and 120 mmHg during night. |