Endoscopic and medical therapy of gastric antral vascular ectasia: case series and review of available methods

Authors

ŠRAMKOVÁ Michaela KROUPA Radek DASTYCH Milan KONEČNÝ Štefan KUNOVSKÝ Lumír DOLINA Jiří

Year of publication 2021
Type Article in Periodical
Magazine / Source Gastroenterologie a hepatologie
MU Faculty or unit

Faculty of Medicine

Citation
Web https://www.csgh.info/cs/clanek/endoskopicka-a-medikamentozni-terapie-cevnich-ektazii-zaludecniho-antra-gave-serie-kazuistik-a-prehled-metod-11235
Doi http://dx.doi.org/10.48095/ccgh2021221
Keywords gastric antral vascular ectasia; argon plasma coagulation; endoscopic band ligation; thalidomide; gastrointestinal bleeding
Description Gastric antral vascular ectasia (GAVE) is an uncommon diagnosis leading to chronic iron deficiency anaemia caused by occult or overt gastrointestinal bleeding. The mainstay of the therapy is based on endoscopic therapy using endoscopic thermal methods – particularly argon plasma coagulation and others – radiofrequency ablation, coagulation or cryotherapy. Endoscopic band ligation presents satisfying results as well. Pharmacotherapy aiming at reduction of the development of new vascular lesions and reduction of blood flow in them could be considered in patients refractory to endoscopic treatment. We present a review of available endoscopic and non-endoscopic methods for GAVE therapy and our experience with the therapy of refractory GAVE using a combination of endoscopic methods and thalidomide on case series. The algorithm for GAVE therapy is proposed.

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