Effect of shift-work on 7-day/24-h ambulatory blood pressure monitoring



Year of publication 2021
Type Conference abstract
MU Faculty or unit

Faculty of Medicine

Description Objective: Poor health outcomes associated with shift work include increased risks of diabetes mellitus, dyslipidemia, hypertension, heart disease, peptic ulcer disease, depression and cancer. The aim of the study was to compare the 7-day/24-h blood pressure ambulatory monitoring in healthy subjects and nurses working in day and night work shifts. Design and method: We examined 297 healthy subjects and 6 women (age 33 ± 2 years, body weight 70 ± 21 kg, mean height 165 ± 5 cm) and 4 men (age 28 ± 7 years, body weight 93 ± 11 kg, mean height 185 ± 5 cm), in days with day work, days with night work and free days, using Medical Instruments TM2431 (A and D, Japan). Results: The mean (±SD) of sleep hours in the week in 10 nurses during 7-day/24-h blood pressure monitoring was 37.75 ± 2.75 h per week. The mean of 7-day/24-h ambulatory blood pressure monitoring was SBP 126 ± 7.6 mmHg, of DBP 76 ± 5 mmHg, of HR 74 ± 5 bpm. Contrary to healthy subjects, in all shift workers we have found the disturbences in circadian rhythm according the day and night shifts. The seven day/24-hour systolic blood pressure profiles vary from 110 to 140 mmHg and we can not use reference values for 24-h ambulatory blood pressure monitoring, while there is impairment in circadian rhythm because of irregular night work. The similar condition is valid for diastolic blood pressure. Longitudinal monitoring could be implemented more generally to assess inter-individual responds to shift work. Conclusions: Seven day/24-h ambulatory blood pressure monitoring in night shift workers showed impairment of circadian rhythm and BP vary according to the work depending on different working shifts, and decrease of sleep hours. Further work is also needed to determine whether there may be shift work schedules that are less detrimental than others.

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