Hepatitis E - epidemiology and clinical course in the largest cohort in the Czech Republic.
| Authors | |
|---|---|
| Year of publication | 2022 |
| Type | Article in Periodical |
| Magazine / Source | Archives of Medical Science |
| MU Faculty or unit | |
| Citation | |
| Web | https://www.archivesofmedicalscience.com/Hepatitis-E-epidemiology-and-clinical-course-in-the-largest-cohort-in-the-Czech-Republic,152338,0,2.html |
| Doi | http://dx.doi.org/10.5114/aoms/152338 |
| Keywords | therapy; epidemiology; Czech Republic; Eastern Europe; hepatitis E; hepatitis E virus; viral zoonosis |
| Description | Introduction: The majority of hepatitis E (HE) reports come from Western Europe. The aim of the study was to describe the typical epidemiological and clinical characteristics of HE in the Czech Republic. Material and methods: The retrospective analysis of 173 patients with HE. Results: At least 90% of cases were autochthonous (HEV-3 genotype). Seventeen patients were treated with ribavirin. Five underwent liver transplants because of fulminant HE. We noted neurological symptomatology in 9 cases. Six patients developed chronic HE. Conclusions: There is a possibility of severe health complications caused by the hepatitis E virus in the Czech Republic. |