Hepatitis E - epidemiology and clinical course in the largest cohort in the Czech Republic.
|Druh||Článek v odborném periodiku|
|Časopis / Zdroj||Archives of Medical Science|
|Fakulta / Pracoviště MU|
|Klíčová slova||therapy; epidemiology; Czech Republic; Eastern Europe; hepatitis E; hepatitis E virus; viral zoonosis|
|Popis||Introduction: The majority of hepatitis E (HE) reports come from Western Europe. The aim of the study was to describe the typical epidemiological and clinical characteristics of HE in the Czech Republic. Material and methods: The retrospective analysis of 173 patients with HE. Results: At least 90% of cases were autochthonous (HEV-3 genotype). Seventeen patients were treated with ribavirin. Five underwent liver transplants because of fulminant HE. We noted neurological symptomatology in 9 cases. Six patients developed chronic HE. Conclusions: There is a possibility of severe health complications caused by the hepatitis E virus in the Czech Republic.|