Hepatitis E - epidemiology and clinical course in the largest cohort in the Czech Republic.
| Autoři | |
|---|---|
| Rok publikování | 2022 |
| Druh | Článek v odborném periodiku |
| Časopis / Zdroj | Archives of Medical Science |
| Fakulta / Pracoviště MU | |
| Citace | |
| www | https://www.archivesofmedicalscience.com/Hepatitis-E-epidemiology-and-clinical-course-in-the-largest-cohort-in-the-Czech-Republic,152338,0,2.html |
| Doi | http://dx.doi.org/10.5114/aoms/152338 |
| Klíčová slova | therapy; epidemiology; Czech Republic; Eastern Europe; hepatitis E; hepatitis E virus; viral zoonosis |
| Popis | Introduction: The majority of hepatitis E (HE) reports come from Western Europe. The aim of the study was to describe the typical epidemiological and clinical characteristics of HE in the Czech Republic. Material and methods: The retrospective analysis of 173 patients with HE. Results: At least 90% of cases were autochthonous (HEV-3 genotype). Seventeen patients were treated with ribavirin. Five underwent liver transplants because of fulminant HE. We noted neurological symptomatology in 9 cases. Six patients developed chronic HE. Conclusions: There is a possibility of severe health complications caused by the hepatitis E virus in the Czech Republic. |