Heart rate and increased intravascular volume

Authors

SOUČEK Miroslav KÁRA Tomáš JURÁK Pavel HALÁMEK Josef ŠPINAROVÁ Lenka MELUZÍN Jaroslav TOMAN Jiří ŘIHÁČEK Ivan ŠUMBERA Josef FRÁŇA Petr

Year of publication 2003
Type Article in Periodical
Magazine / Source Physiol. Research
MU Faculty or unit

Faculty of Medicine

Citation
Field Cardiovascular diseases incl. cardiosurgery
Keywords kidneys; heart rate; atrial mechanisms; intravascular volume; breathing
Description The objective was to establish whether an intravascular volume increase leads to a heart rate (HR) incerase without increased sympahetic tonus. HR changes at rest and at deep breathing (6/min - simulated increase of atrial filling pressure) were measured in patients after heart transplantation. Evaluation of dependency of HR changes on breathing depth was done through a new time series methodology. The data was evaluated through graphs displaying a significant increase in the graph area at deep breathing, when compared with breathing at rest (p<0.01). We presume that an incease in HR corresponds to increased intravascular volume and malfunctioning kidneys.
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