Dendritic cell counts and their subsets during treatment of multiple myeloma
| Authors | |
|---|---|
| Year of publication | 2007 |
| Type | Article in Periodical |
| Magazine / Source | Neoplasma |
| MU Faculty or unit | |
| Citation | |
| Web | http://www.neoplasma.sk/ |
| Field | Oncology and hematology |
| Keywords | dendritic cells; multiple myeloma; flow cytometry |
| Description | Dendritic cells are highly specialised antigen-presenting cells, which can be used for immunotherapy trials. Functionally normal DCs play a critical role in the activation and potentiation of tumour antigen-specific responses, but in some cases they can be defective. The aim of study were analysis of phenotype, finding of differences and/or functional defects in DCs generated from multiple myeloma and monoclonal gammopathy of unknown significance subjects when compared with healthy volunteers under serum-free and/or autologous conditions. |