Možnosti modulace ATRA-indukované diferenciace neuroblastomových a meduloblastomových buněčných linií působením LOX/COX inhibitorů.

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Title in English	Possibilities to modulate ATRA-induced cell differentiation of neuroblastoma and medulloblastoma cell lines by LOX/COX inhibitors.
Authors	RÉDOVÁ Martina CHLAPEK Petr LOJA Tomáš ZITTERBART Karel HERMANOVÁ Markéta ŠTĚRBA Jaroslav VESELSKÁ Renata
Year of publication	2009
Type	Article in Proceedings
Conference	XXXIII. Brněnské onkologické dny - edukační sborník
MU Faculty or unit	Faculty of Science
Citation
Field	Oncology and hematology
Keywords	neuroblastoma; medulloblastoma; established cell lines; caffeic acid; celecoxibe; all-trans retinoic acid; cell differentiation
Description	A detailed study of the effect of combined application of the LOX/COX inhibitors with ATRA in established neuroblastoma and medulloblastoma cell lines was performed using MTT-assay, immunoblotting, and flow cytometry.
Related projects:	Molecular basis of cell and tissue regulations Modulace antineoplastického efektu retinoidů LOX/COX inhibitory na modelu dětských solidních nádorů: in vitro studie Molecular mechanisms of the cell proliferation and differentiation