Systematic Comparisons of Electrocardiographic Morphology Increase the Precision of QT Interval Measurement
| Authors | |
|---|---|
| Year of publication | 2009 |
| Type | Article in Periodical |
| Magazine / Source | PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY |
| MU Faculty or unit | |
| Citation | |
| Doi | http://dx.doi.org/10.1111/j.1540-8159.2009.02185.x |
| Field | Other medical specializations |
| Keywords | thorough QT |
| Description | Decreased intrasubject variability of QTc values is needed to increase the power and reduce the size of the so-called thorough QT studies. One source of QTc variability is the lack of systematic measurements when electrocardiograms (ECG) with closely matching morphologies are not measured in an exactly corresponding way. The inaccuracy can be eliminated by postprocessing of QT measurements by ECG pattern matching. This study tested the effects of pattern matching in ECG measurements in two populations of healthy subjects (n = 48 56) and in a population of patients with advanced Parkinson |