Systematic Comparisons of Electrocardiographic Morphology Increase the Precision of QT Interval Measurement

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HNATKOVA Katerina SMETANA Peter TOMAN Ondřej BAUER Axel SCHMIDT G. MALIK Marek

Rok publikování 2009
Druh Článek v odborném periodiku
Časopis / Zdroj PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
Fakulta / Pracoviště MU

Lékařská fakulta

Citace
Doi http://dx.doi.org/10.1111/j.1540-8159.2009.02185.x
Obor Ostatní lékařské obory
Klíčová slova thorough QT
Popis Decreased intrasubject variability of QTc values is needed to increase the power and reduce the size of the so-called thorough QT studies. One source of QTc variability is the lack of systematic measurements when electrocardiograms (ECG) with closely matching morphologies are not measured in an exactly corresponding way. The inaccuracy can be eliminated by postprocessing of QT measurements by ECG pattern matching. This study tested the effects of pattern matching in ECG measurements in two populations of healthy subjects (n = 48 56) and in a population of patients with advanced Parkinson

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