Informace o projektu
The impact of derivation substrate on differentiation of human embryonic stem cells for the cell therapy
- Kód projektu
- MUNI/IGA/1332/2021
- Období řešení
- 1/2022 - 12/2022
- Investor / Programový rámec / typ projektu
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Masarykova univerzita
- Interní grantová agentura MU
- Fakulta / Pracoviště MU
- Lékařská fakulta
Human embryonic stem cells (hESC) are able to differentiate into every cell type in the human body (e.g., neural, cardiac, or retinal cells), which may then be the basis for cell therapies. Our aim is to examine how substrate used for derivation of hESC influences their differentiation propensity, which is critical for the potential application of hESC in a clinical setting. Here, we study the capacity of hESC derived on different substrates to produce cells of all three embryonal lineages.
Publikace
Počet publikací: 2
2023
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Truncated vitronectin with E-cadherin enables the xeno-free derivation of human embryonic stem cells
Scientific Reports, rok: 2023, ročník: 13, vydání: 1, DOI
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Vitronectin is a xeno-free and defined surface for the derivation of human embryonic stem cells
Rok: 2023, druh: Konferenční abstrakty