Trefoil Factor 1 as a marker of mucosal damage of the gastrointestinal tract in children with sepsis
Autoři | |
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Rok publikování | 2013 |
Druh | Článek v odborném periodiku |
Časopis / Zdroj | Biomarkers |
Fakulta / Pracoviště MU | |
Citace | |
Doi | http://dx.doi.org/10.3109/1354750X.2013.783116 |
Obor | Mikrobiologie, virologie |
Klíčová slova | Children; gut; mortality; sepsis; trefoil factor |
Popis | Intestinal ischemia and reperfusion is a common pathway for many diseases in children. The objective of our study was an analysis of Trefoil factor 1 levels dynamics in patients with SIRS or septic condition during a 5-day period. Analysis of TFF1 levels dynamics revealed that TFF1 levels kept steady state during the 5-day period. TFF1 levels were similar in patients with SIRS, sepsis and severe sepsis. Significantly higher levels of TFF1 were in patients with septic shock and MODS. |