Changes in Hematologic and Coagulation Profiles in Rabbits with Right-ventricle Pacing
| Autoři | |
|---|---|
| Rok publikování | 2016 |
| Druh | Článek v odborném periodiku |
| Časopis / Zdroj | Folia Medica |
| Fakulta / Pracoviště MU | |
| Citace | |
| Doi | http://dx.doi.org/10.1515/folmed-2016-0013 |
| Obor | Farmakologie a lékárnická chemie |
| Klíčová slova | aPTT; activated partial thromboplastin time; FDP-fibrin degradation products |
| Popis | Objectives: The aim of this study was to evaluate changes in hematology and coagulation in rabbits with right-ventricle pacing without medication. Animals and methods: Blood was collected from ten non-anesthetized male rabbits from the jugular vein before and one month after pacemaker placement. Total erythrocyte, leukocyte and platelet count, hemoglobin, hematocrit and diff erential leukocyte count were done on automatic veterinary flow cytometry hematologic analyzer. Prothrombin time, activated partial thromboplastin time, fibrinogen level, D-dimers and kaolin-activated thromboelastography was measured from citrated blood.Results: We found an increase in red blood cell mass and decrease in platelet count, while coagulation tests did not diff er between samplings. |