Lack of omalizumab efficacy in severe atopic dermatitis with extremely elevated EgE levels: two case reports and a literature rewiev
| Název česky | Nedostatečný efekt omalizumabu u těžké atopické dermatitidy s extrémními hosnotami IgE: popis dvou případů a přehled literatury |
|---|---|
| Autoři | |
| Rok publikování | 2019 |
| Druh | Článek v odborném periodiku |
| Časopis / Zdroj | Acta dermatovenerologica Alpina, Pannonica et Adriatica |
| Fakulta / Pracoviště MU | |
| Citace | |
| www | http://dx.doi.org/10.15570/actaapa.2019.22 |
| Doi | http://dx.doi.org/10.15570/actaapa.2019.22 |
| Klíčová slova | atopic dermatitis; treatment; omalizumab |
| Popis | The authors present two cases of severe atopic dermatitis with extremely elevated IgE levels treated with omalizumab. The effect of this treatment was completely unconvincing in both patients, most likely because of extremely elevated IgE values, which could not be eliminated by omalizumab. Our observation is consistent with earlier published literature reporting that omalizumab as a treatment for atopic dermatitis seems to work better in patients with lower levels of IgE antibodies. |