Maytenus macrocarpa (Ruiz & Pav.) Briq.: Phytochemistry and Pharmacological Activity

Varování

Publikace nespadá pod Lékařskou fakultu, ale pod Farmaceutickou fakultu. Oficiální stránka publikace je na webu muni.cz.

Autoři	MALANÍK Milan TREML Jakub RJAŠKOVÁ Veronika TÍŽKOVÁ Karolína KAUCKÁ Petra KOKOŠKA Ladislav KUBATKA Peter ŠMEJKAL Karel
Rok publikování	2019
Druh	Článek v odborném periodiku
Časopis / Zdroj	Molecules
Fakulta / Pracoviště MU	Farmaceutická fakulta
Citace
Doi	http://dx.doi.org/10.3390/molecules24122288
Klíčová slova	dihydro-beta-agarofuran sesquiterpene; folk medicine; Maytenus macrocarpa; rheumatism; triterpene
Popis	Maytenus macrocarpa (Celastraceae) is a tree native to Amazonia. Its roots, leaves, bark, and combinations of these are used in traditional medicine mainly to treat rheumatism and, to a lesser extent, to heal wounds and to combat bronchitis and diarrhea. To date, mainly triterpenes and dihydro-beta-agarofuran sesquiterpenes were isolated from M. macrocarpa. Extracts and selected pure compounds isolated from the leaves, roots, and stem bark showed antibacterial, antiviral, antiparasitic, anti-inflammatory, and cytotoxic activities in vitro. The aim of this review is to summarize the available ethnobotanical, phytochemical, and pharmacological information about this traditional Amazonian medicinal tree, as well as to attract the attention of phytochemists and pharmacognosists to this potentially interesting source of ethnopharmaceuticals.