THE ROLE OF PROBIOTICS IN THE EFFECTIVENESS OF TREATMENT AGAINST HELICOBACTER PYLORI: RESULTS OF THE EUROPEAN REGISTRY ONTHE MANAGEMENT OF HELICOBACTER PYLORI INFECTION (HP-EUREG)

Autoři	DEZA Casas ALCEDO J BLASCO M Lafuente LORENTE J López PÉREZ-AÍSA Á PAVONI M SALACINO TEPEŠ B JONAITIS FERNÁNDEZ M Castro CARRASCO M Pabón HUERGA A Keco VOYNOVAN I FERNÁNDEZ DE PIÉROLA L Bujanda LUCENDO A J JURECIC N Brglez DENKOVSKI M PHULL P SÁEZ Rodrigo LANAS A MARTÍNEZ-DOMÍNGUEZ S J HUGUET J M BORDIN GASBARRINI A KUPCINSKA J BABAYEVA G GRIDNYEV O LEJA M ROKKAS T PINTO R Marcos LERANG F BOLTIN D PAPP V TONKIC A SMITH S SIMSEK H VENERITO M BOYANOVA L MILIVOJEVIC V KUNOVSKÝ Lumír MATYSIAK-BUDNIK T MARLICZ W DOULBERIS M CATALA A Cano VILLALBA L Hernández RUIZ L Moreira NYSSEN O P MEGRAUD F MORAIN GISBERT J
Rok publikování	2023
Druh	Konferenční abstrakty
Fakulta / Pracoviště MU	Lékařská fakulta
Citace
Popis	Introduction: There are doubts about the effectiveness of concomitant use of probiotics (PB) in the treatment of Helicobacter pylori infection. Objective: To determine whether the use of PB improves the effectiveness of eradication treatments used in Europe. Aims & Methods: Prospective, multicentre, non-interventional, prospective registry (Hp-EuReg) of the clinical practice of European gastroenterologists. Data were collected in an e-CRD in AEG-REDCap from 2013 to 2021. All data from countries with at least 30 cases undergoing eradication therapy and at least 1 with associated PB were included, using patients without PB as controls and grouping by geographical region. Modified intention-to-treat (mITT) analyses were performed, as well as multivariate analysis, assessing factors associated with treatment effectiveness.