Primary Breast Sarcoma: A Two-Centre Analysis and Review of Literature

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ŽATECKÝ Jan COUFAL Oldřich FABIAN Pavel HOLÁNEK Miloš SEHNALKOVA Eva BURKOŇ Petr

Rok publikování 2023
Druh Článek v odborném periodiku
Časopis / Zdroj BREAST CARE
Fakulta / Pracoviště MU

Lékařská fakulta

Citace
www https://karger.com/brc/article/18/4/262/843569/Primary-Breast-Sarcoma-A-Two-Centre-Analysis-and
Doi http://dx.doi.org/10.1159/000530934
Klíčová slova Primary breast sarcoma; Prognostic factors; Two-centre analysis
Popis Introduction: Primary breast sarcoma is a very rare malignant type of breast tumours with an incidence of 0.1% of all primary breast malignancies. Methods: We present a retrospective analysis of the case series from two hospitals in the Czech Republic with a review of the diagnostic and treatment approach to primary breast sarcomas with an analysis of published prognostic factors. Results: Eleven patients were included in the study, 9 women and 2 men. Statistical evaluation revealed that tumour size (p = 0.1964), grade (p = 0.1667), margin distance (p = 0.5403), mitotic activity (p = 0.8577), or age (p = 0.7822) were not prognostic factors in our cohort. Conclusion: The analysis did not prove any of the factors, such as age, tumour size, grade, or mitotic activity, to be statistically significant prognostic factors. Based on the literature review, the most common published prognostic factors are tumour size, margin status, and grade, but the results are ambiguous.

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