Mitochondrial uncoupling protein in brown adipocytes differentiated in cell culture

Varování

Publikace nespadá pod Lékařskou fakultu, ale pod Přírodovědeckou fakultu. Oficiální stránka publikace je na webu muni.cz.

Autoři	KOPECKÝ Jan BAUDYŠOVÁ Marie PAVELKA Stanislav ZANOTTI Francesco JANÍKOVÁ Dagmar HOUŠTĚK Josef
Rok publikování	1991
Druh	Článek v odborném periodiku
Časopis / Zdroj	Journal of Cellular Biochemistry [IF=2.778 (1990)]
Fakulta / Pracoviště MU	Přírodovědecká fakulta
Citace
Obor	Biochemie
Klíčová slova	Biogenesis; brown adipose tissue; thermogenic mitochondria; uncoupling protein
Popis	Differentiation of precursor cells isolated from mouse brown adipose tissue was studied in cell culture, in order to characterize the biogenesis of unique thermogenic mitochondria. Synthesis of mitochondrial uncoupling protein (UCP), F1-ATPase, and cytochrome oxidase was examined by L-[35S]methionine labeling and immunoblotting. In these cells, it was possible, by using norepinephrine, to induce specifically the synthesis of the UCP but not of F1-ATPase or cytochrome oxidase.