The effectiveness of dried cranberries ( Vaccinium macrocarpon) in men with lower urinary tract symptoms

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VIDLAR A. VOSTALOVA J. ULRYCHOVA Jitka STUDENT V. STEJSKAL D. REINBACH R. VRBKOVÁ J. RŮŽIČKA Filip ŠIMÁNEK Vilím

Rok publikování 2010
Druh Článek v odborném periodiku
Časopis / Zdroj British Journal of Nutrition
Fakulta / Pracoviště MU

Lékařská fakulta

Citace
Doi http://dx.doi.org/10.1017/S0007114510002059
Obor Biochemie
Klíčová slova Vaccinium macrocarpon; Cranberries; Urinary tract disorders; Prostatitis; Prostate-specific antigen
Popis The objective of the present study was to evaluate the efficacy and tolerability of cranberry (Vaccinium macrocarpon) powder in men at risk of prostate disease with LUTS, elevated prostate-specific antigen (PSA), negative prostate biopsy and clinically confirmed chronic non-bacterial prostatitis. Forty-two participants received either 1500 mg of the dried powdered cranberries per d for 6 months (cranberry group; n 21) or no cranberry treatment (control group; n 21). Physical examination, International Prostate Symptom Score, quality of life (QoL), five-item version of the International Index of Erectile Function (IIEF-5), basic clinical chemistry parameters. There was no statistically significant improvement in the control group. The results of the present trial are the first firm evidence that cranberries may ameliorate LUTS, independent of benign prostatic hyperplasia or C-reactive protein level.

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