Czech Infrastructure for Integrative Structural Biology (CIISB)
- Kód projektu
- LM2015043
- Období řešení
- 1/2016 - 12/2019
- Investor / Programový rámec / typ projektu
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Ministerstvo školství, mládeže a tělovýchovy ČR
- Velké infrastruktury pro výzkum, vývoj a inovace
- Fakulta / Pracoviště MU
- Středoevropský technologický institut
The Czech Infrastructure for Integrative Structural Biology (CIISB) is a distributed infrastructure of the core facilities and central laboratories of CEITEC (Central European Institute of Technology, Brno) and BIOCEV (Biotechnology and Biomedicine Centre, Vestec, Prague-West) providing expertise and access to technologies used for integrative approaches to structural analysis of biologically important cellular components and macromolecules - proteins, nucleic acids, and their complexes. CIISB, equipped with the cutting-edge technologies (total investments will exceed 750 mil. CZK by the end of 2015), will offer access to the equipment and expertise in the following fields: high-field NMR spectroscopy; high throughput crystallization of biological macromolecules; X-ray diffraction techniques; Bio-SAXS measurements; AFM imaging; characterization of proteins, nucleic acids and complexes by biophysical methods including microcalorimetry, dynamic light scattering, and surface plasmon resonance; high-end cryo-electron microscopy and tomography allowing studies of cellular structures, organelles, and biomacromolecular complexes by 3D imaging; protein expression in eukaryotic cells; high-end mass spectrometry characterization of biomacromolecules; determination of protein post-translational modifications; MS-based peptide mapping/sequencing; high throughput sequencing and proteomic services. CIISB infrastructure aims to provide a high quality open access services in provision of methods and techniques on a level of national and trans-national importance. CIISB as National Affiliated Center is a part of the ESFRI projects INSTRUCT.
Publikace
Počet publikací: 312
2023
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Aerosol-assisted sol–gel synthesis of mesoporous Ag–Ta–SiO2 catalysts for the direct upgrading of ethanol to butadiene
RSC Sustainability, rok: 2023, ročník: 1, vydání: 3, DOI
2022
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A release of Ti-ions from nanostructured titanium oxide surfaces
Surfaces and Interfaces, rok: 2022, ročník: 29, vydání: April 2022, DOI
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Airborne Preparation of Small Gold Nanoparticles Dispersed on Mesoporous Silica for the Catalytic Oxidation of Glycerol to Dihydroxyacetone
ACS Applied Nano Materials, rok: 2022, ročník: 5, vydání: 12, DOI
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Quantitation of Human 14-3-3ζ Dimerization and the Effect of Phosphorylation on Dimer-monomer Equilibria
Journal of Molecular Biology, rok: 2022, ročník: 434, vydání: 7, DOI
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Toward understanding the kinetics of disassembly of ferritins of varying origin and subunit composition
Applied Materials Today, rok: 2022, ročník: 28, vydání: AUG, DOI
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Transcriptomic and proteomic profiling of peptidase expression in Fasciola hepatica eggs developing at host's body temperature
SCIENTIFIC REPORTS, rok: 2022, ročník: 12, vydání: 1, DOI
2021
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Acetylace 7-hydroxy skupiny dibenzocyklooktadienových lignanů zvyšuje inhibici P-glykoproteinu
Rok: 2021, druh: Konferenční abstrakty
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Consolidation of Bioglass (R) 45S5 suspension through cold isostatic pressing
Ceramics International, rok: 2021, ročník: 47, vydání: 3, DOI
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Death Receptor 5 (TNFRSF10B) Is Upregulated and TRAIL Resistance Is Reversed in Hypoxia and Normoxia in Colorectal Cancer Cell Lines after Treatment with Skyrin, the Active Metabolite of Hypericum spp.
Cancers, rok: 2021, ročník: 13, vydání: 7, DOI
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Eudiplozoon nipponicum (Monogenea, Diplozoidae) and its adaptation to haematophagy as revealed by transcriptome and secretome profiling
BMC Genomics, rok: 2021, ročník: 22, vydání: 1, DOI