Molecular Typing of Syphilis-Causing Strains Among Human Immunodeficiency Virus-Positive Patients in Antwerp, Belgium

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MIKALOVÁ Lenka GRILLOVÁ Linda OSBAK Kara STROUHAL Michal KENYON Chris CRUCITTI Tania ŠMAJS David

Rok publikování 2017
Druh Článek v odborném periodiku
Časopis / Zdroj Sexually Transmitted Diseases
Fakulta / Pracoviště MU

Lékařská fakulta

Citace
Doi http://dx.doi.org/10.1097/OLQ.0000000000000600
Obor Genetika a molekulární biologie
Klíčová slova Treponema pallidum
Popis Centers for Disease Control and Prevention and sequencing-based treponeme typing was used to analyze 72 blood samples, collected from human immunodeficiency virus and syphilis co-infected patients during 2014 to 2015 in Antwerp, Belgium. Twenty-nine (40.3%) isolates were polymerase chain reaction positive for Treponema pallidum, and all tested were macrolide-resistant. Four genotypes were identified by sequencing-based typing including two new genotypes, U4NR8 and SU9R8, whereas enhanced Centers for Disease Control and Prevention typing revealed 7 subtypes.
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