Effect of methamphetamine and fluoxetine combination on behavioural activity in wistar albino rats
| Název česky | Vliv kombinace fluoxetinu a metamfetaminu na behaviorání aktivitu u potkana kmene Wistar |
|---|---|
| Autoři | |
| Rok publikování | 2002 |
| Druh | Článek v odborném periodiku |
| Časopis / Zdroj | Bratislavské lekárské listy |
| Fakulta / Pracoviště MU | |
| Citace | |
| www | http://www.bmj.cz |
| Obor | Farmakologie a lékárnická chemie |
| Klíčová slova | fluoxetine; methamphetamine; behaviour; rat |
| Popis | Locomotor / exploratory behavioural changes were followed in Wistar rats pretreated with methamphetamine, fluoxetine or their combination. An "open field" (Acti-track, Panlab, Spain) was used as the tracking arena. Methamphetamine significantly increased all measured behavioural parameters while fluoxetine showed inhibitory effects. Pretreatment with combination of these drugs resulted in a more profound inhibition of locomotor activity than in fluoxetine given alone. |
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